A key pharmaceutical intermediate used in the manufacture of ketoconazole and related azole antifungal APIs.
1-Acetyl-4-(4-Hydroxyphenyl)piperazine (AHPP) is a key pharmaceutical intermediate used primarily in the synthesis of ketoconazole, a broad-spectrum azole antifungal API. Its reliable supply and consistent purity directly affect the quality of the downstream product.
Also known as 4-(1-acetylpiperazin-4-yl)phenol, AHPP contributes the acetyl-piperazine / phenol fragment that forms part of the azole antifungal scaffold. Consistent quality at this stage is critical to efficient, high-yield downstream manufacturing.
Provides the acetyl-piperazine / phenol fragment used to build the azole antifungal scaffold.
A key intermediate step in the manufacture of ketoconazole APIs.
Consistent quality upstream ensures consistent downstream API.
Intermediate for ketoconazole and related azole antifungal APIs.
Used as an impurity / reference standard in analytical work.
Specialty pharmaceutical and fine-chemical formulations.
| CAS No. | 67914-60-7 |
|---|---|
| Molecular Formula | C12H16N2O2 |
| Molecular Weight | ≈ 220.27 g/mol |
| Appearance | White to off-white crystalline powder / solid |
| Assay / Purity | As per agreed specification (high-purity grades available) |
| Category | API intermediate |
High-purity grades supplied to your agreed specification, with COA and SDS on every shipment.
Supplied in HDPE / fibre drums or as required. Store in a cool, dry, ventilated area away from incompatible materials.
Dependable, high-purity intermediate supply for synthesis programmes.
Flexible batch sizes to support scale-up manufacturing.
COA and SDS on every shipment, with global export.
It is a key pharmaceutical intermediate, used primarily in the synthesis of ketoconazole and related azole antifungal APIs.
High-purity grades supplied to your agreed specification, with COA.
Yes — consistent, documented purity with flexible batch sizes for reliable downstream production.
Yes — global export with COA and SDS on every shipment.
Get specifications, COA and pricing with flexible batch sizes. Our team responds within one business day.
