Salcaprozate Sodium (SNAC)
An oral absorption enhancer that enables delivery of peptides and other large molecules through the oral route.
The enabling excipient behind oral peptide delivery
Salcaprozate Sodium — widely known as SNAC — is an oral absorption enhancer that makes it possible to deliver large, poorly-absorbed molecules such as peptides through the oral route. Historically, peptide drugs could only be given by injection because they are broken down in the gut and cannot easily cross the intestinal wall. SNAC changes that.
Acting as an enabling excipient, SNAC transiently and reversibly increases the permeability of the gastrointestinal lining and helps protect the co-formulated drug in the stomach, allowing meaningful amounts to reach the bloodstream. It is the technology that underpins modern oral peptide formulations, and demand has grown rapidly alongside oral GLP-1 and other biologic therapies.
How it works
Increases GI permeability
Transiently and reversibly increases trans-epithelial permeation in the GI tract.
Protects the peptide
Creates a favourable local micro-environment that protects the peptide from degradation.
Localised & reversible
The effect is localised and reversible — the barrier restores after absorption.
Key applications
Oral peptide delivery
Oral delivery of peptides and macromolecular drugs, e.g. GLP-1 analogues.
Improved bioavailability
Improving oral bioavailability of poorly-permeable APIs.
Biologic dosage forms
Solid oral dosage development for biologics and specialty molecules.
Product specifications (typical)
| CAS No. | 203787-91-1 |
|---|---|
| Molecular Formula | C15H20NNaO4 |
| Molecular Weight | ≈ 301.30 g/mol |
| Appearance | White to off-white powder |
| Assay / Purity | As per agreed specification (typically ≥ 98%) |
| Category | Oral absorption / permeation enhancer |
Specifications are typical and can be tailored to agreed customer requirements. COA, SDS and technical specification supplied with every batch.
Quality & compliance
- Manufactured under strict quality systems
- COA, SDS and technical specification with every batch
- Consistent purity and particle characteristics
- Documentation support for regulatory filings
Packaging & storage
Supplied in food/pharma-grade packaging (e.g. HDPE containers) or as required. Store in a cool, dry place, protected from moisture and light.
Why choose Narmada Organics
Reliable, scalable supply of a specialty enabling excipient in rising demand.
Consistent purity and particle characteristics, batch to batch.
COA, SDS and regulatory support for development and commercial needs.
Frequently asked questions
What is Salcaprozate Sodium (SNAC) used for?
It is an oral absorption enhancer that helps large, poorly-absorbed molecules such as peptides cross the intestinal wall — enabling oral (tablet/capsule) versions of drugs that would otherwise need injection.
Is this the same excipient used in oral peptide products?
Yes — SNAC is the established permeation-enhancer technology behind modern oral peptide formulations, including oral GLP-1 approaches.
Do you provide a COA and regulatory documentation?
Yes. Every batch ships with a Certificate of Analysis and Safety Data Sheet, and we can support your regulatory filings.
Can you supply bulk / export quantities?
Yes. We supply from development to commercial scale and export globally. Share your quantity and specification for a quote.
Building an oral peptide formulation?
Get SNAC specifications, COA and pricing for development and commercial supply. Our team responds within one business day.